This guide contains information about places where you can stop for the night when driving from Knoxville, Tennessee to Grand Canyon, Arizona. Total distance for the trip is around 1806 miles with a driving time of approximately 1 day 2 hours. Cities and towns with hotels that are on the fastest route between Knoxville and Grand Canyon are listed below. (Driving times are approximate and will vary with traffic and weather conditions.)

102 miles from Knoxville (1 hour 35 mins)
1706 miles from Grand Canyon (1 day 0 hours)
180 miles from Knoxville (2 hours 41 mins)
1627 miles from Grand Canyon (23 hours 1 min)
391 miles from Knoxville (5 hours 42 mins)
1415 miles from Grand Canyon (19 hours 58 mins)
528 miles from Knoxville (7 hours 41 mins)
1288 miles from Grand Canyon (18 hours 7 mins)
595 miles from Knoxville (8 hours 37 mins)
1213 miles from Grand Canyon (17 hours 5 mins)
677 miles from Knoxville (9 hours 46 mins)
1132 miles from Grand Canyon (15 hours 58 mins)
767 miles from Knoxville (11 hours 2 mins)
1039 miles from Grand Canyon (14 hours 38 mins)
857 miles from Knoxville (12 hours 19 mins)
951 miles from Grand Canyon (13 hours 23 mins)
967 miles from Knoxville (13 hours 54 mins)
840 miles from Grand Canyon (11 hours 48 mins)
1115 miles from Knoxville (15 hours 59 mins)
695 miles from Grand Canyon (9 hours 46 mins)
1224 miles from Knoxville (17 hours 30 mins)
582 miles from Grand Canyon (8 hours 12 mins)
1396 miles from Knoxville (19 hours 54 mins)
411 miles from Grand Canyon (5 hours 52 mins)
1476 miles from Knoxville (21 hours 3 mins)
334 miles from Grand Canyon (4 hours 49 mins)
1534 miles from Knoxville (21 hours 49 mins)
272 miles from Grand Canyon (3 hours 57 mins)
1661 miles from Knoxville (23 hours 34 mins)
145 miles from Grand Canyon (2 hours 14 mins)
1719 miles from Knoxville (1 day 0 hours)
78.8 miles from Grand Canyon (1 hour 29 mins)
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You'll be given this information with the available room rates after you select a hotel and specify dates. Many hotels have cancellation penalties associated with their best rates. Most offer "Book Now and Pay Later" options that are less restrictive, but slightly more expensive.